The ASPREE study will recruit 19,000 healthy participants, both males and females,
aged 70 years or older.
Approximately 6,500 participants will be recruited in the United States through
clinical trials centres in Minneapolis, Pittsburgh, Chicago and Wake Forest and
primary care clinics in San Antonio.
In Australia, approximately 12,500 participants will be recruited through general
practice in Melbourne, regional Victoria, Tasmania and the Australian Capital Territory.
People are eligible to take part in this study if they are:
- aged 70 years or over
- willing and able to provide informed consent
People cannot take part if they:
- have blood vessel disease.
- have a serious illness.
- are allergic to aspirin or cannot take it.
- have had or are at risk of serious bleeding.
- are taking other 'blood thinning' medication.
- have seriously impaired mental or physical function.
To find eligible participants in Australia, researchers will recruit General Practitioners
(GPs) to join the study as co-investigators.
GPs will send invitation letters to their patients who may be eligible. The letter
will include some information about the study and ask that interested people respond
by calling 1800 728 745 (free call number).
People who respond will be interviewed on the phone and asked some basic questions
about their medical history and the medications they take. After this phone screening
process, people who are eligible and wish to continue will start the Enrolment or
‘run-in’ phase of the trial. At the end of the Enrolment phase, people willing to
continue will be randomized, or randomly assigned, to take either aspirin or placebo
and followed up for an average of five years.
How to join?
To find out if the ASPREE team is recruiting in your area please register your interest
or refer to the following:
If the team
is recruiting in your area please look out for a letter from your GP about ASPREE.
If you are a GP who is interested in becoming a co-investigator please register your interest and one of our staff will contact you.